Behind Whole Exome Sequencing (WES)

Test Code : T1195

Whole Exome Sequencing (WES) analyses approximately 20,000 protein-coding genes in a single test to identify genetic variants associated with inherited disorders. By focusing on the exome, where most disease-causing variants occur, WES provides comprehensive insights for diagnosing rare and hereditary conditions.

Blood Sample

Peripheral blood sample collected for comprehensive genomic testing.

DNA Extraction

High-quality genomic DNA is isolated from the collected sample.

Whole Exome Sequencing

Approximately 20,000 protein-coding genes are analysed using advanced NGS technology.

Clinical Report

Expert interpretation identifies clinically relevant genetic variants associated with inherited disorders.

Comprehensive
Genetic Testing
for Inherited Disorders

Whole Exome Sequencing (WES) analyzes the protein-coding regions of genes to identify genetic variants associated with inherited disorders.

Test Details

Whole Exome Sequencing

Comprehensive Genomic Test


Test Code
T1195
TAT
18 Days
Sample Type
Peripheral Blood
(EDTA sample)

How much is Test Coverage?

Protein-coding regions (exons)

across ~20,000 genes

Disease-associated genetic variants

Selected splice-site regions

relevant to disease

Few of Genes Analyzed

BRCA1 / BRCA2

Hereditary Cancer Syndromes

COL1A1 / COL1A2

Connective Tissue Disorders

POLG

Mitochondrial Disorders

& thousands more clinically relevant genes

When Should I Order WES?

Developmental delay / Intellectual disability
Epilepsy with unknown cause
Neuromuscular disorder
Multiple congenital anomalies
Rare or undiagnosed disease
Strong family history

What can WES Detect?

01

Pathogenic & likely Pathogenic Variants

02

Variants of Uncertain Significance (VUS)

03

Inherited Genetic Disorders

04

Carrier status for selected genetic conditions

Benefits of WES

Why Clinicians Choose Whole Exome Sequencing

Comprehensive Analysis

Comprehensive analysis in a single test to evaluate nearly all protein-coding genes.

Rare Disease Diagnosis

Supports accurate diagnosis of inherited and rare genetic disorders.

Clinical Management

Enables clinicians to make informed treatment and management decisions.

Genetic Counselling

Supports family planning, carrier screening and genetic counselling.

Advanced Technology

Our advanced sequencing workflow combines cutting-edge technology with clinically validated databases for accurate genomic insights.

Next-Generation Sequencing (NGS)

High-quality sequencing across clinically relevant coding regions.

High-quality Sequencing Coverage

Deep sequencing ensures reliable detection of clinically relevant variants.

Clinical Database Analysis

Variant interpretation using established clinical databases and evidence.

Genetic Counseling Recommended

Helps explain test results

Clarifies inheritance patterns

Assesses implications for family members

Supports informed healthcare decisions

Difficult Case, Choose WES

Broad coverage across ~20,000 genes

Advanced NGS technology

Clinically relevant variant interpretation

Supports personalized patient care

Unlock Comprehensive Genetic Insights with Whole Exome Sequencing

Analyse approximately 20,000 protein-coding genes in a single test to identify genetic variants associated with inherited disorders. Download the brochure or connect with our experts to learn more.