Behind ThyroTrack

Developed by MedGenome , ThyroTrack is a next-generation sequencing (NGS)-based thyroid prognostication panel designed to uncover the genetic profile of thyroid nodules using Thyroid FNAC in RNA Later fluid or FFPE Block samples. By analysing clinically relevant mutations and gene fusions, ThyroTrack helps clinicians improve the evaluation of indeterminate thyroid nodules and supports informed treatment decisions.

MedGenome

Developer of ThyroTrack and leader in advanced clinical genomics.

Sample Collection

Thyroid FNAC in RNA Later fluid or FFPE Block collected for molecular analysis.

NGS Analysis

46 genes for SNVs & InDels and 23 fusion genes are analysed using advanced NGS technology.

Clinical Report

Comprehensive genomic findings support thyroid nodule risk assessment.

Understanding Bethesda Classification

Thyroid nodules are initially classified using the Bethesda System based on FNAC findings. While most nodules are clearly benign or malignant, approximately 10–30% remain indeterminate and require advanced molecular testing such as ThyroTrack for better clinical decision-making.

50–70% of Nodules

Clearly Classified

FNAC successfully classifies most thyroid nodules as benign or malignant, enabling standard clinical management.

  • Benign diagnosis
  • Malignant diagnosis
  • Standard treatment pathway
  • Routine clinical follow-up
10–30% of Nodules

Indeterminate Nodules

Molecular profiling with ThyroTrack helps evaluate indeterminate thyroid nodules by detecting clinically significant mutations and gene fusions.

  • Supports difficult diagnoses
  • Improves risk stratification
  • Guides surgical decisions
  • Reduces unnecessary procedures

46

Genes for SNVs & InDels

23

Fusion Genes

69

Total Genetic Targets

How CanAssistBreast Testing Works

From tumour tissue analysis to AI-driven risk prediction, every step is designed to deliver accurate and personalized recurrence risk assessment.

01

Thyroid Nodule

A thyroid nodule is detected during clinical examination or imaging.

02

FNAC Cytology

Fine Needle Aspiration Cytology (FNAC) is performed to evaluate the nodule.

03

Indeterminate Result

FNAC shows an indeterminate or suspicious Bethesda classification.

04

ThyroTrack Test

NGS analyses 46 genes for SNVs & InDels and 23 fusion genes.

05

Clinical Decision

Molecular findings support diagnosis and personalized treatment planning.

What's Included in ThyroTrack?

ThyroTrack uses targeted Next-Generation Sequencing (NGS) to analyse clinically significant genes associated with thyroid cancer. The panel detects both small genetic variants and clinically actionable gene fusions for comprehensive molecular profiling.

46 Genes

SNVs & InDels

Detection of clinically relevant Single Nucleotide Variants and Insertions/Deletions.

BRAF RAS PI3K TP53 PTEN TERT AKT1 EIF1AX +38 More
23 Genes

Fusion Analysis

Identification of clinically significant gene fusions associated with thyroid malignancies.

RET NTRK ALK ROS1 BRAF MET FGFR2 PPARG +15 More

Make Confident Decisions with ThyroTrack

Improve thyroid nodule evaluation with ThyroTrack's advanced molecular testing. Reduce diagnostic uncertainty, support personalized patient management, and enable confident clinical decision-making with accurate genomic insights.