Assess 14 HLH-associated genes inclusive of the major drivers of HLH (PRF1, STXBP2, and UNC13D) from a simple blood sample.
Advanced Genomics Laboratory
Peripheral Blood
Comprehensive Genomic Analysis
Expert Interpretation
The HLH Gene Panel assesses 14 clinically relevant genes, including the major genetic drivers associated with Hemophagocytic Lymphohistiocytosis (HLH).
These genes are among the most commonly implicated in inherited Hemophagocytic Lymphohistiocytosis.
Additional genes evaluated to support comprehensive genetic assessment of HLH.
Hemophagocytic Lymphohistiocytosis (HLH) is a rare and life-threatening hyperinflammatory syndrome in which the immune system becomes overactive, resulting in excessive inflammation, tissue damage and, if left untreated, can lead to organ failure or death.
From a simple blood sample to an expert-reviewed clinical report, the HLH Gene Panel follows a comprehensive genomic workflow for accurate molecular diagnosis.
Peripheral blood sample collected for molecular genetic analysis.
High-quality genomic DNA is extracted from the blood sample.
Next-Generation Sequencing (NGS) analyzes the 14 HLH-associated genes.
Clinical experts review and interpret the detected variants.
Comprehensive genomic report delivered within 19 Working Days.
Advance HLH diagnosis with precise molecular testing. Reduce diagnostic uncertainty, facilitate early diagnosis, and guide personalized treatment decisions through reliable genomic findings.