Ovarian Cancer

Precision Oncology for Ovarian Cancer

Ovarian cancer develops when abnormal cells grow uncontrollably in one or both ovaries. Precision oncology and comprehensive genomic profiling help identify actionable biomarkers, enabling personalized treatment strategies and improving patient outcomes.

Early Detection
Precision Medicine
Better Outcomes
Ovarian Cancer

What is Ovarian Cancer?

Ovarian cancer is the abnormal growth of cells in one or both ovaries. It is often called a "silent disease" because symptoms are usually vague and may not appear until the cancer has advanced.

Precision oncology and molecular profiling help identify genetic alterations that support personalized treatment decisions and targeted therapies.

Begins in the ovaries
Often diagnosed at a later stage
Genomic testing supports personalized treatment

Symptoms

  • Pelvic, abdominal or back pain
  • Abdominal bloating or swelling
  • Feeling full quickly
  • Loss of appetite
  • Fatigue
  • Pain during sexual intercourse
  • Abnormal vaginal bleeding
  • Diarrhoea or constipation
  • Frequent urination
  • Unexplained weight loss

Risk Factors

  • Age 60 years or older
  • Family history of ovarian, breast, uterine or colorectal cancer
  • BRCA1 or BRCA2 gene mutations
  • Endometriosis
  • Obesity
  • Early menstruation (before age 12)
  • Late menopause (after age 50)
  • Never been pregnant
Diagnosis & Treatment

Diagnosis and Treatment Options

Accurate diagnosis and molecular profiling help determine the stage of ovarian cancer and guide individualized treatment.

Diagnosis

1
Pelvic Examination

Initial examination to identify pelvic abnormalities.

2
Blood Tests & Imaging

Blood tests together with transvaginal ultrasound, CT, MRI or PET scans evaluate ovarian masses.

3
Biopsy

Tissue examination confirms ovarian cancer and supports treatment planning.

Treatment Options

Surgery

Removal of the ovaries and other affected reproductive organs where appropriate.

Chemotherapy

Anti-cancer medicines destroy rapidly growing cancer cells.

Hormone Therapy

Medicines block hormones that may promote tumour growth.

Immunotherapy

Helps the immune system recognize and attack cancer cells.

Targeted Therapy

Precision medicines target specific genetic alterations within tumour cells.

Prognosis

Survival Outcomes

Prognosis depends on the stage of diagnosis, tumour biology, and response to treatment.

Overall Survival

35.2%

5-Year Survival Rate

Median Survival

38

Months

Treatment Outlook

  • Earlier diagnosis improves survival
  • Surgery combined with chemotherapy is the standard treatment
  • Genomic profiling supports targeted treatment selection

Frequently Asked Questions

Epithelial ovarian cancer: The most common type arising from the outer surface of the ovary.

Germ cell tumours: Rare cancers arising from egg-producing cells, usually affecting children and young adults.

Stromal ovarian cancer: A rare cancer that develops from the connective tissue of the ovary.

Stage I: Cancer is limited to the ovaries or fallopian tubes.

Stage II: Cancer has spread to nearby pelvic organs.

Stage III: Cancer has spread to abdominal lymph nodes or upper abdomen.

Stage IV: Cancer has spread to distant organs.

Early symptoms are often vague and non-specific, making early diagnosis difficult. In addition, there is currently no effective routine screening test for ovarian cancer in the general population.

Recommended Tests

BRCA1 / BRCA2 Analysis
Neuberg Diagnostics
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